Quantifying lymphocyte vacuolization serves as a measure of CLN3 disease severity
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چکیده
منابع مشابه
Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection
BACKGROUND Respiratory viral infections follow an unpredictable clinical course in young children ranging from a common cold to respiratory failure. The transition from mild to severe disease occurs rapidly and is difficult to predict. The pathophysiology underlying disease severity has remained elusive. There is an urgent need to better understand the immune response in this disease to come up...
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Background and purpose: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by synovitis, inflammation, and joint destruction that if not well controlled can destroy cartilage, bone, ligaments and tendons, and in some cases cause disability. The aim of this study was to evaluate the possible role of the ratio of neutrophil-lymphocyte (NLR) as an inflammatory mar...
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Acute kidney injury (AKI) may be the real epidemic kidney disease,1 and practicing nephrologists have long known that patients with reduced GFR are more likely to experience AKI, particularly in the elderly.2 Surprisingly, this relationship had not been quantified rigorously until recently. For example, the widely disseminated Clinical Practice Guidelines for Chronic Kidney Disease by the Natio...
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In malaria-endemic areas, Plasmodium falciparum parasitemia is common in apparently healthy children and severe malaria is commonly misdiagnosed in patients with incidental parasitemia. We assessed whether the plasma Plasmodium falciparum DNA concentration is a useful datum for distinguishing uncomplicated from severe malaria in African children and Asian adults. P. falciparum DNA concentration...
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A study was carried out to examine the validity of social dysfunctioning as a measure of severity of illness. Modified version of KAS, R2 inventory was used to measure social functioning. Since there can be no absolute measure of severity of psychiatric illness, the validity was tested through indirect means. It was decided that if the scores on social dysfunctioning were higher amongst the men...
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ژورنال
عنوان ژورنال: JIMD Reports
سال: 2020
ISSN: 2192-8312,2192-8312
DOI: 10.1002/jmd2.12128